Saccharomyces cerevisiae-based system for studying clustered DNA damages
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چکیده
منابع مشابه
Saccharomyces cerevisiae-based system for studying clustered DNA damages
DNA-damaging agents can induce clustered lesions or multiply damaged sites (MDSs) on the same or opposing DNA strands. In the latter, attempts to repair MDS can generate closely opposed single-strand break intermediates that may convert non-lethal or mutagenic base damage into double-strand breaks (DSBs). We constructed a diploid S. cerevisiae yeast strain with a chromosomal context targeted by...
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ژورنال
عنوان ژورنال: Radiation and Environmental Biophysics
سال: 2010
ISSN: 0301-634X,1432-2099
DOI: 10.1007/s00411-010-0303-3